Guillotine | Binding of Isaac: Rebirth Wiki | Fandom
· Defeat Isaac as Judas Guillotine is an unlockable passive item. 1 Effects 2 Notes 3 Synergies 4 Interactions 5 Ingame Footage 6 Trivia 7 Seeds Isaac''s head rotates around his body and can be used to inflict contact damage similar to a Cube of Meat. Blocking tears with Isaac''s head does not damage Isaac. His tears still originate from his head, so the line of fire is no longer constant while ...